热敏灸联合神经根阻滞对神经根型颈椎病外周血细胞因子的影响研究

Study on the effect of thermal moxibustion combined with nerve root block on peripheral blood cell factor of nerve root type cervical spondylosis

目的:神经根型颈椎病作为一种临床常见病,其发病率逐年上升且趋向年轻化,严重影响着人们的日常生活和正常工作,本研究旨在探讨热敏灸联合神经根阻滞对神经根型颈椎病外周血细胞因子的影响。方法:随机选取2017年1月—2018年1月我院收治的并确诊为神经根型颈椎病患者共120例,依据治疗方法将这些患者分为热敏灸联合DSA引导下神经根阻滞术组(A组,n=30)、热敏灸疗法组(B组,n=30)、神经根阻滞术组(C组,n=30)和常规针刺治疗组(D组,n=30)四组,对比四组的临床治疗效果A组、B组、C组患者治疗的总有效率均显著高于D组(P<0.05),而A组患者治疗的总有效率又显著高于B组、C组(P<0.05),但B组和C组患者治疗的总有效率之间的差异不显著(P>0.05);治疗前四组患者的外周血清TNF-α、IL-6水平之间的差异均不显著(P>0.05),治疗后A组、B组、C组患者的外周血清TNF-α、IL-6水平均显著低于D组(P<0.05),而A组患者的外周血清TNF-α、IL-6水平又均显著低于B组、C组(P<0.05),但B组和C组患者的外周血清TNF-α、IL-6水平之间的差异均不显著(P>0.05)。结论:热敏灸联合神经根阻滞能够有效降低神经根型颈椎病外周血细胞因子水平,值得临床进一步推广。

Objective:Cervical spondylosis of nerve root type is a kind of clinical common disease and its incidence is rising year by year and tends to be younger,which seriously affects people's daily life and work,this study is to investigate the block effect of thermal moxibustion combined nerve root block on peripheral blood cell factors on cervical spondylosis of nerve root type.Methods:A total of 120 patients with cervical spondylosis of nerve root type diagnosed and treated in our hospital from January 2017 to January 2018 were randomly selected and divided into thermal moxibustion combined DSA guided by nerve root blockage technique group(group A,n=30),thermal moxibustion therapy group(group B,n=30),nerve root block group(group C,n=30)and conventional acupuncture treatment group(group D,n=30)four groups,and the clinical treatment effect of four groups was compared.Results:The total effective rate of treatment of Group A,group B,and group C was significantly higher than that of group D(P<0.05),and the total effective rate of treatment group A was significantly higher than that of group B and group C(P<0.05),but the difference between the total effective rate of treatment group B and C group was not significant(P>0.05);Before treatment,the differences of TNF-α,IL-6 level in peripheral blood of patients of four groups were not significant(P>0.05),after treatment,TNF-α,IL-6 level in peripheral blood of patients of group A,group B and C group of patients were significantly lower than those of group D(P<0.05),and TNF-α,IL-6 level in peripheral blood of patients of group A was significantly higher than that of group B and group C(P<0.05),but the difference between the total effective rate of treatment group B and C group was not significant(P>0.05).Conclusion:Thermal moxibustion combined nerve root block had significant effect on peripheral blood cell factors on cervical spondylosis of nerve root type,which was worthy of clinical promotion.