非布司他的合成方法综述

A Review of Synthesis of Febuxstat

非布司他是一种被广泛用于治疗痛风和高尿酸血症的药物。介绍了目前已报道的非布司他合成路线,并对其进行初步评价,以期找到能够工业化生产的较佳合成工艺。

Febuxstat is widely used for treating gout and hyperuricemia.Current existing synthetic routes of Febuxstat were introduced,analyzed,discussed and appraised in this thesis in order to search for a suitable synthetic route for large scale industrization.