色谱分析中的串联技术

Tandem technologies in chromatographic analysis

样品中物质信息的获取离不开分离和检测,对于复杂样品的分析,简单的一维色谱方法常常难以完成所有组分的分离和鉴定。为此,多种色谱串联技术引起了人们的广泛关注。色谱串联技术包括柱串联技术、检测器串联技术、多维色谱等。该文详细介绍了以上3种串联技术(不包括色谱-质谱联用技术)自2010年以来的最新研究进展,以及这些技术在获取样品中更加全面和精准的信息方面的典型应用。最后对色谱串联分析技术的发展进行了总结和展望。

The acquisition of chemical compounds information from samples depends on the separation as well as detection techniques.Usually,it is difficult to achieve the separation and identification of all components in complex samples by a simple one-dimensional chromatographic method.Thus,tandem technologies,which mainly include column tandem connection techniques,detector tandem connection techniques,and multidimensional chromatography,have aroused widespread interest.In this paper,advances in the three aforementioned tandem techniques(not including chromatography tandem mass spectrometry)since 2010 are discussed.Typical applications for obtaining more comprehensive and accurate information from samples are also reviewed.Finally,the development of chromatographic tandem technologies is summarized and future prospects are examined.