卢立康唑的波谱学特征和结构确证

Spectral Analysis and Structural Elucidation of Luliconazole

用红外吸收光谱、紫外吸收光谱、核磁共振(NMR)波谱(包含~1H NMR、^(13)C NMR、DEPT135、~1H-~1H COSY、~1H-^(13)C HMQC和~1H-^(13)C HMBC)、质谱、差示扫描量热分析、X-射线粉末衍射和元素分析等方法对卢立康唑进行了结构分析.对卢立康唑所有的~1H和^(13)C NMR信号进行了归属,并通过多种谱学技术确证了卢立康唑的结构.

Infrared spectra,ultraviolet spectra,nuclear magnetic resonance(NMR)spectra(i.e.,1H NMR,13C NMR,DEPT135,1H-1H COSY,1H-13C HMQC and 1H-13C HMBC)and mass spectra of luliconazole were collected and used to characterize the compound.Differential scanning calorimetry,X-ray power diffraction and elementary analysis were also performed.All 1H and 13C NMR signals of the compound were assigned.The structure of the compound was determined.