摘要
在L-蛋氨酸(L-Met)的导向下,可控制备了一种单层中空CaCO_3微球。考察了L-Met的加入量、CO_2流速和反应温度等重要参数对CaCO_3形貌、尺度和晶相的影响。作为一种客体分子载体,该单层中空CaCO_3微球可负载罗丹明B(RhB),得到一种发光复合材料(RhB@hollow-CaCO_3)。RhB@hollow-CaCO_3)对A-549肺癌细胞(A549 LCCs)和HO8910人卵巢癌细胞(HO8910 OCCs)表现出良好的生物相容性。
Mono-shelled hollow sphere CaCO3 microspheres were prepared in the presence of L-methionine(L-Met)via a CO2 bubbling method;after that,the effects of L-Met adding amount,CO2 flow rate,and temperature on morphology,size,and phase composition of CaCO3 have been systemically explored.As a potential guest molecule carrier,the as-synthesized hollow sphere CaCO3 microspheres could load with rhodamine B(RhB)to prepare a novel luminescent composite material(RhB@hollow-CaCO3).This luminescent composite material not only presented good biocompatibility to the A-549 lung cancer cells(A-549 LCCs)and HO8910 ovarian cancer cells(HO8910 OCCs),but also had the ability of luminescence in above cells.
作者
刘江
沙峰
杨廷玉
马良
张建斌
LIU Jiang;SHA Feng;YANG Ting-Yu;MA Liang;ZHANG Jian-Bin(College of Chemical Engineering,Inner Mongolia University of Technology,Hohhot 010051,China;Inner Mongolia Engineering Research Center for CO2 Capture and Utilization,Hohhot 010051,China;Key Laboratory of Coal?鄄based CO2 Capture and Geological Storage,China University of Mining and Technology,Xuzhou,Jiangsu 221008,China)
出处
《无机化学学报》
SCIE
CAS
CSCD
北大核心
2018年第9期1688-1700,共13页
Chinese Journal of Inorganic Chemistry
基金
国家自然科学基金(No.21666027)、内蒙古自治区“草原英才”和内蒙古科委攻关资助项目。
