氨氯地平联合缬沙坦治疗社区老年原发性高血压合并糖尿病的效果观察

Effect observation of amlodipine combined with valsartan in the treatment of elderly patients with essential hypertension combined with diabetes mellitus

目的:探讨社区老年原发性高血压合并糖尿病患者采取氨氯地平联合缬沙坦治疗的临床效果。方法:收治社区老年原发性高血压合并糖尿病患者60例,随机分为两组。对照组给予氨氯地平治疗,观察组给予氨氯地平联合缬沙坦治疗,比较两组治疗前后血糖、血压水平。结果:治疗后,观察组舒张压、收缩压及空腹血糖、空腹胰岛素、餐后2 h血糖均低于对照组,差异有统计学意义(P<0.05)。结论:社区老年原发性高血压合并糖尿病患者采取氨氯地平联合缬沙坦治疗的临床效果显著。

Objective:To investigate the clinical effect of amlodipine combined with valsartan in the treatment of elderly patients with essential hypertension combined with diabetes mellitus.Methods:60 cases of elderly patients with essential hypertension combined with diabetes mellitus were divided into two groups randomly.The control group was given amlodipine treatment,while the observation group was given amlodipine combined with valsartan,the blood glucose and blood pressure levels were compared between the two groups before and after treatment.Results:After treatment,the diastolic blood pressure and systolic blood pressure in the observation group were lower than those in the control group,the difference was statistically significant(P<0.05).After treatment,the fasting blood glucose,fasting insulin and postprandial 2 h blood glucose in the observation group were lower than those in the control group,the difference was statistically significant(P<0.05).Conclusion:The clinical effect of amlodipine combined with valsartan was significant in the treatment of elderly patients with essential hypertension combined with diabetes mellitus.