干扰素α-1b与孟鲁司特钠并用治疗小儿喘息性支气管炎疗效观察

Efficacy of interferon alpha ＿1b combined with montelukast sodium in the treatment of asthmatic bronchitis in children

目的:探讨干扰素α-1b联合孟鲁司特钠治疗小儿喘息性支气管炎的疗效。方法:收治喘息性支气管炎患儿90例,随机分为对照组和试验组,各45例对照组采用孟鲁司特钠治疗,试验组采用干扰素α-1b联合孟鲁司特钠治疗。比较两组疗效。结果:试验组治疗有效率明显高于对照组,且不良反应发生率低于对照组(P<0.05)。结论:干扰素α-1b与孟鲁司特钠并用治疗小儿喘息性支气管炎临床疗效更好,能够提高治疗有效率,并且可以减少治疗过程中出现的不良反应。

Objective:To investigate the efficacy of interferon alpha-1b combined with montelukast sodium in the treatment of asthmatic bronchitis in children.Methods:90 children with asthmatic bronchitis were selected,they were randomly divided into the control group and the experimental group with 45 cases in each group,the control group was treated with montelukast sodium,and the experimental group was treated with interferon alpha-1b combined with montelukast sodium.Results:The effective rate of the experimental group was significantly higher than that of the control group,and the incidence of adverse reactions was lower than that of the control group(P<0.05).Conclusion:The effect of interferon alpha-1b and montelukast sodium in the treatment of asthmatic bronchitis in children is better than montelukast,it can improve the efficiency of treatment and reduce the adverse reactions during the treatment.