连续性静脉-静脉血液滤过治疗重症慢性肾脏病临床疗效

Clinical efficacy of continuous venous venous hemofiltration in the treatment of severe chronic kidney disease

目的:探讨连续性静脉-静脉血液滤过治疗重症慢性肾脏病的疗效。方法:收治慢性肾衰竭-尿毒症脑病患者47例,随机分为对照组(15例)和观察组(32例)。对照组慢性肾衰竭-尿毒症脑病患者给予血液透析+血液灌流治疗,观察组慢性肾衰竭-尿毒症脑病患者给予连续性静脉-静脉血液滤过治疗。结果:观察组慢性肾衰竭-尿毒症脑病患者治愈率高于对照组(P<0.05)。治疗15天后,观察组慢性肾衰竭-尿毒症脑病患者血尿素氮、血肌酐、甲状旁腺素、血碳酸氢根、β2-微球蛋白浓度下降优于对照组(P<0.05)。结论:连续性静脉-静脉血液滤过治疗尿毒症脑病患者,有利于降低并发症发生率,具有更高的临床疗效,预后情况良好,能提高患者生存质量。

Objective:To evaluate the efficacy of continuous venous venous hemofiltration in the treatment of severe chronic kidney disease.Methods:47 patients with chronic renal failure-uremia encephalopathy were selected,they were randomly divided into the control group(with 15 cases)and the observation group(with 32 cases).The control group was treated with hemodialysis combined with hemoperfusion,and the observation group was treated with continuous venous venous hemofiltration.Results:The cure rate of the observation group was higher than that of the control group(P<0.05).After treatment for 15 days,the concentration of blood urea nitrogen,serum creatinine,parathyroid hormone,blood bicarbonate andβ2-microglobulin in the observation group were lower than those in the control group(P<0.05).Conclusion:Continuous venous venous hemofiltration in the treatment of patients with uremia encephalopathy can reduce the incidence of complications,have a higher clinical effect,good prognosis,and improve the life quality of the patients.