半夏泻心汤加味治疗幽门螺杆菌感染相关性胃病的临床观察

Observation on treating gastropathy infected by Hp with the Banxia Xiexin decoction

目的:研究半夏泻心汤加味对幽门螺杆菌感染相关性胃病的治疗效果。方法:选取2016年2月-2017年3月收治的接受半夏泻心汤加味治疗的22例幽门螺杆菌感染相关性胃病患者为研究组,同期选取接受常规西医治疗的22例患者为对照组,观察两组治疗有效率、症状积分及不良反应发生情况。结果:研究组显效率达72.73%,明显高于对照组40.91%;治疗总有效率是95.45%,同样明显高于对照组72.73%,差异有统计学意义(P<0.05);研究组胃黏膜修复显效率为77.27%,明显的高于对照组的45.45%;研究组胃黏膜修复总有效率是100.00%,同样明显的高于对照组的77.27%,差异有统计学意义(P<0.05);研究组治疗后症状积分明显的优于对照组,且临床症状消失时间显著短于对照组,差异有统计学意义(P<0.05);研究组不良反应发生率为18.18%,而对照组达59.09%,研究组显著低于对照组,差异有统计学意义(P<0.05)。结论:幽门螺杆菌感染相关性胃病给予半夏泻心汤加味中药治疗效果显著,能够显著降低不良反应的发生,值得推广应用。

Objective:To study the effects of the Banxia Xiexin decoction(半夏泻心汤)on gastropathy infected by Hp.Methods:22 cases in the study group was treated with the Banxia Xiexin decoction;and 22 patients in the control group was given conventional western medicine.Results:The efficiency in the study group was 72.73%,was significantly higher than 40.91%in the control group;the total efficiency was 95.45%in the study group,and significantly higher than 72.73%in the control group(P<0.05).The efficiency of gastric mucosal repair in the study group was 77.27%,was significantly higher than 45.45%in the control group;the total efficiency of gastric mucosal repair was 100.00%in the study group,and significantly higher than 77.27%in the control group(P<0.05).The symptom scores in the study group was significantly better than the control group;and the disappearance time of clinical symptoms was significantly shorter than the control group(P<0.05);the incidence of adverse reactions in the study group was 18.18%,and significantly lower than 59.09%in the control group(P<0.05).Conclusion:The Banxia Xiexin decoction on gastropathy infected by Hp shows a significant effect,can significantly reduce adverse reactions,and is worth popularizing.