宫颈癌三维后装治疗与传统二维后装治疗剂量学参数的对比研究

A comparative study on dose parameters of treating cervical cancer by three-dimensional afterloading therapy and traditional two-dimensional afterloading therapy

目的:探讨宫颈癌三维后装治疗与传统二维后装治疗剂量学参数的对比。方法:随机抽取2015年3月-2017年3月40例行宫颈癌放疗治疗患者,使用后装治疗计划系统进行计划设计,观察患者在三维后装治疗下与传统二维后装治疗下的靶区覆盖指数、危及器官体积指数与靶区适形指数。结果:两组患者的靶区覆盖指数无显著变化,且三维后装治疗与传统二维后装治疗的2次计划与1次计划的靶区剂量与危及器官剂量无显著变化,不具有统计学意义(P>0.05);三维后装的靶区适形指数明显优于二维后装,二维后装的膀胱、直肠体积指数明显高于三维后装,二者差异具有统计学意义(P<0.05)。结论:运用三维后装治疗宫颈癌能够对患者的膀胱与直肠形成更好的保护,但二者在靶区剂量与对危及器官的保护方面不存在显著变化。

Objective:To compare the dose parameters between three-dimensional afterloading therapy and traditional twodimensional afterloading therapy on treating cervical cancer.Methods:40 cases were randomly selected and given afterloading therapy plan system.The target coverage index,the organ volume index and the target-conformal index between three-dimensional afterloading therapy and traditional two-dimensional afterloading therapy were observed.Results:There was no significant change of the target coverage index,the target dose and the dose of the risk organs between the two times plan in groups(P>0.05).The target-conformal index of threedimensional afterloading therapy was significantly better than the traditional two-dimensional afterloading therapy.The rectal volume index of traditional two-dimensional afterloading therapy was significantly higher than the three-dimensional afterloading therapy;and the difference was statistically significant(P<0.05).Conclusion:The three-dimensional afterloading in treating cervical cancer can form a better protection for bladder and rectum.There was no significant difference of target dose and the protection of the organs in groups.