聚乳酸全降解血管支架的专利技术

An overview of patented technology for fully-degradable polylactic acid stents

背景:专利分析有助于了解相关领域专利技术的发展脉络和关键技术,提高对该领域技术发展的把握能力。目的:探讨聚乳酸全降解血管支架领域专利申请态势及技术发展路线。方法:检索聚乳酸全降解血管支架领域全球专利申请,从申请量年度趋势、主要申请人分布、专利技术分支、重要申请人分析等方面对专利技术进行分析,重点分析共混改性聚乳酸血管支架主体材料核心专利、专利技术发展演进。结果与结论:聚乳酸全降解血管支架是目前血管支架领域的重点研究方向。材料、工艺方法和结构设计是该领域专利的主要申请方向,其中以对材料的研究改进申请量最多,也是该领域起步最早的技术分支。在技术需求方面,提高支架材料的力学性能、控制支架降解速率、改善药物控释性能是主要的关注热点。

BACKGROUND:Research on patented technology contributes to understanding the development and key technology of the related field,and enhances the ability to grasp the technological developments in this field.OBJECTIVE:To investigate the patent application situation and technical development route in the field of fully-degradable polylactic acid stents.METHODS:We searched the patent applications for fully-degradable polylactic acid stents all over the world,and analyzed relevant information in the following aspects:annual application quantity,the distribution of the main applicants,the branches of the patent technology,the analysis of the important applicants.Afterwards,we focused on the blending modification of polylactic acid stents,and analyzed its core patents and the development of patented technology.RESULTS AND CONCLUSION:The fully-degradable polylactic acid stent is the focus direction of current research in the field of vascular stents.Materials,technique and structural design are the main aspects for patent applications in this field.Among them,the application for improvement of materials is the most frequently conducted,which is the earliest branch of technology in this field.In terms of technical requirements,improving the mechanical properties of scaffolds,controlling the degradation rate of stents,and improving the controlled release of drugs are the main concerns.