连续性血液净化用于重症肺炎合并多器官功能衰竭中的作用研究

目的:研究连续性血液净化用于重症肺炎合并多器官功能衰竭中的应用价值。方法:以2016年10月-2017年10月期间在我院进行治疗的重症肺炎合并多器官功能衰退的患者作为研究对象,总计48例。对所有患者进行基础治疗,同时再对其进行连续性血液净化治疗。观察患者治疗前与治疗后24h、48h心率、血压、呼吸频率、血常规、凝血功能、血气分析以及肾功能和电解质等各项指标的变化,并使用APACHEII对患者病情变化情况进行评估。结果:与治疗前对比,治疗后24h、48h患者的心率、血压、呼吸频率、血常规、凝血功能、血气分析以及肾功能和电解质等各项指标变化情况均具有较为明显的优势,数据对比为P<0.05,存在统计学意义;总计12例患者死亡,36例患者成功救治,分别将其设为生存组以及死亡组,生存组APACHEII评分显著低于死亡组,数据对比为P<0.05。结论:连续性血液净化用于重症肺炎合并多器官功能障碍中能够明显改善治疗疗效,提高患者生存率,而APACHEII评分则能够作为患者预后效果的判断标准。

Objective:To discuss the continuous blood purification to severe pneumonia combining multiple organ failure.Methods:Choosed 48 cases of MOF patients from Oct.2016 to Oct.2017 to take routine treatment with continuous blood purification.Observed the heart rate,blood pressure,breathing rate,blood routine,blood clotting function,blood gas analysis,and kidney function and electrolytes after 24h,48h.And tae the APACHEII assessment.Results:The results of index of heart rate,blood pressure,breathing rate,blood routine,blood clotting function,blood gas analysis after 24h,48h had different from before treatmet.And there were 12 cases dead,36 cases successful rescue.Conclusion:Using continuous blood purification to severe pneumonia combining multiple organ failure can improve survival rate and use APACHEII as the criterion.