期刊文献+

依那普利与苯磺酸氨氯地平联合治疗老年肾性高血压患者的临床疗效评价 被引量:1

下载PDF
导出
摘要 目的:将依那普利联合苯磺酸氨氯地平使用于老年肾性高血压患者的治疗中,评价并分析临床疗效。方法:2015年11月至2017年10月本医院所纳入治疗的70例老年肾性高血压患者作为本文实验资料,分组方法参考患者的治疗用药不同,依那普利用于参照组(n=35),依那普利联合苯磺酸氨氯地平用于实验组(n=35),观察及统计2组患者的治疗有效合计率、治疗之前和治疗之后的尿蛋白定量数值、血肌酐数值、尿素氮数值。结果:参照组患者的治疗有效合计率对比实验组患者相关数据,P<0.05,表现出数值之间对比的统计学意义,参照组患者治疗之后的尿蛋白定量数值、血肌酐数值、尿素氮数值对比实验组患者相关数据,P<0.05,表现出数值之间对比的统计学意义。结论:在老年肾性高血压患者的临床治疗中采用依那普利联合苯磺酸氨氯地平呈现较优的临床疗效,体现重要应用价值及意义。 Objective:to evaluate and analyze the clinical curative effect of enalopril combined with amlodipine,which is used in the treatment of elderly patients with renal hypertension.Methods:in November 2015 to October 2017 in this hospital in treatment of 70 cases of senile renal hypertensive patients as the experimental data,this paper grouping method reference for the treatment of patients with medication,enalaprilat is used in the control group(n=35),joint enalaprilat benzene sulfonic acid amlodipine used in the experimental group(n=35),observation and statistics of the treatment of patients with total effective rate of two groups before and after treatment,treatmen t of urine protein quantitative numerical,serum creatinine and urea nitrogen values.Result:the treatment of patients with the control group total effective rate of contrast group patients,P<0.05,show the comparison between the numerical statistical significance,quantitative numerical control group patients after treatment of urinary protein,serum creatinine and urea nitrogen value s compared with the experimental group patients with relevant data,P<0.05,show the comparison between the numerical statistical significance.Conclusion:in the clinical treatment of senile patients with renal h ypertension,the clinical efficacy of enalopril combined with amlodipine of benzene sulfonate is presented,which shows the important application value and significance.
出处 《湖南中医药大学学报》 CAS 2018年第A01期74-74,共1页 Journal of Hunan University of Chinese Medicine
关键词 依那普利 苯磺酸氨氯地平 肾性高血压 老年人 Enalapril Amlodipine benzene sulfonate Renal hypertension The elderly
  • 相关文献

二级参考文献29

  • 1汪锦丹.左旋氨氯地平联合依那普利治疗高血压合并心衰临床分析[J].中外医学研究,2013,11(20):49-50. 被引量:6
  • 2谌贻璞.慢性肾脏病高血压的治疗目标及药物应用[J].临床内科杂志,2005,22(11):726-728. 被引量:26
  • 3张大勇,李德才,蒋涛,王庆旭,刘思泰,唐焕君,舒艳,王永春.雷米普利降低高血压房颤发生率以及改善左房内径的临床研究[J].中国现代医学杂志,2007,17(16):2021-2023. 被引量:6
  • 4王海燕.肾脏病学.北京:人民卫生出版社,2012.1463-1470.
  • 5Syrigos K N, Karapanagiotou E, Boura P, et al. Bevacizumab- induced hypertension: pathogenesis and management[J].Bio Drugs, 2011, 25(3) : 159-169.
  • 6Mancia G, De Backer G, Dominiezak A, et al. 2007 guidelines for the management of arterial hypertension: the task force for the management of arterial hypertension of the European society of hypertension(ESH) and of the European society of cardiology(ESC) [J].J Hypertens, 2007, 25(5):1105-1187.
  • 7Dussol B, Morange S, Loundoun A, et al. A randomized trial of saline hydration to prevent contrast nephropathy in chronic renal failure patients[J]. Nephrol Dial Transplant, 2006, 21(8) : 2120- 2126.
  • 8Yang YL, Yu LT, Wu ZT, et al. Synergic effects of levamlodipine and bisoprolol on blood pressure reduction and organ protection in spontaneously hypertensive rats[J].CNS Neurosci Ther, 2012,18(6): 471-474.
  • 9Gui H, Guo YF, Liu X, et al. Effects of combination therapy with levamlodipine and bisoprolol on stroke in rats[J].CNS Neurosci Ther, 2013,19(3):178-182.
  • 10刘霖,曹剑,范利,等.阿司匹林联合雷米普利对自发性血压大鼠血小板功能的影响[C]//第二届中国高血压会暨中国医师协会高血压专业委员会年会论文集,2012:40—41.

共引文献15

同被引文献11

引证文献1

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部