不同手术时机治疗老年急性肠梗阻疗效观察及对胃肠功能的影响

目的探讨不同手术时机治疗老年急性肠梗阻的临床疗效。方法以2014年3月至2016年3月于我院进行治疗的120例老年急性肠梗阻患者为研究对象,根据手术时间的不同将其随机分成对照组和观察组,每组60例患者,分析研究两组患者的治疗有效率、术后恢复情况和血清炎症因子含量。结果两组患者的治疗有效率并无显著差异,P>0.05;观察组患者的术后恢复情况明显好于对照组患者,P<0.05,差异显著;术后观察组患者的CRP、TNF-a,MCP-1明显低于对照组,P<0.05,IL-2明显高于对照组,P<0.05。结论急性肠梗阻48h内进行手术治疗,虽不能提高治疗有效率,但是有助于促进胃肠道功能恢复,减少并发症,缓解术后炎症反应。

Objective To investigate the clinical efficacy of different surgical procedures in the treatment of elderly patients with acute intestinal obstruction.Methods 120 elderly patients with acute intestinal obstruction treated in our hospital from March 2014 to March 2016 were studied.According to the different operation time,they were randomly divided into the control group and the observation group,60 patients in each group,the treatment efficiency of the patients in the two groups,postoperative recovery and serum levels of inflammatory factors were analyzed.Results Treatment of the two groups of patients with effective rate had no significant difference,P>0.05;the observation group of patients with postoperative recovery was significantly better than the control group,P<0.05,the difference was significant;the observation group of patients with CRP,after TNF-a,MCP-1 was significantly lower than the control group,P<0.05,IL-2 were significantly higher than the control group,P<0.05.Conclusions Surgical treatment of acute intestinal obstruction in 48h,although not improve the treatment efficiency,but help to promote gastrointestinal function recovery,reduce complications,alleviate postoperative inflammatory response.