PCT检测在老年心衰合并肺炎患者抗炎治疗中的指导意义分析

目的:观察和探讨血清降钙素原(PCT)检测在老年心衰合并肺炎患者的抗炎治疗中的指导意义。方法:选取我院于2017年2月-2018年2月收治的80例老年心衰合并肺炎患者作为研究对象,随机平均分为研究组、对照组,对照组患者采用常规对症治疗,研究组患者在此基础上根据PCT水平采用抗炎治疗,比较两组患者采用不同治疗方式后的临床疗效、治疗时间以及炎症指标变化差异。结果:研究组患者在对照组基础上根据PCT水平指导抗炎治疗后,血清炎症指标(C反应蛋白、红细胞沉降率)显著低于对照组患者,抗炎治疗时间(10.15±2.74)、住院治疗天数(14.15±3.24)显著短于对照组患者(16.82±3.26,16.35±3.42),且总体有效率(95.00%)显著高于对照组(80.00%),具有统计学差异(P<0.05)。结论:血清降钙素原检测在老年心衰合并肺炎患者的抗炎治疗中具有显著指导意义,可有效降低抗生素滥用,提高患者治疗效率和生活质量,值得临床广泛运用。

Objective:To observe and explore the guiding significance of serum calcitonin original(PCT)in anti-inflammatory therapy for elderly patients with heart failure complicated with pneumonia.Methods:A total of 80 elderly patients with heart failure complicated with pneumonia were selected as the study subjects in our hospital from February 2017 to February 2018,and randomly divided into study group and control group.The patients in the control group were treated with routine symptomatic therapy,and the patients in the study group were treated with anti-inflammatory therapy according to the level of PCT.The following ind exes of the two groups were compared,such as clinical efficacy,treatment time,the serum level of inflammation index.Results:The serum inflammatory index(C-reactive protein,erythrocyte sedimentation rate)of the patients in the study group were significantly lower than those in the control group after anti-inflammatory therapy according to the level of PCT.The duration of anti-inflammatory therapy(10.15±2.74)and hospitalization(14.15±3.24)was significantly shorter than that of the control group(16.82±3.26,16.35±3.42)respectively,and the overall effective rate(95.00%)was significantly higher than that of the control group(80.00%),and the difference was statistically significant(P<0.05).Conclusion:PCT index has significant guiding significance in anti-inflammatory therapy for elderly patients with heart failure combined with pneumonia,can effectively reduce the abuse of antibiotics,improve the treatment efficiency and quality of life,which can be wildly application in clinical.