甲状腺功能亢进性心脏病患者右心室功能超声心动图的变化

Echocardiographic changes of right ventricular function in patients with hyperthyroid heart disease

目的观察甲状腺功能亢进性心脏病(简称甲亢心)患者右心室功能超声心动图的变化。方法选择阜阳市人民医院住院诊治的甲亢心患者79例,依据有无发生心力衰竭(简称心衰)分为甲亢心非心衰组(30例),甲亢心心衰组(49例),另外选择甲状腺功能亢进症(简称甲亢)患者30例作为对照组,收集患者的一般资料,行甲状腺功能实验室及心脏超声检查,并给予比较分析。结果甲亢心心衰组患者的年龄、病程、FT3均高于甲亢心非心衰组和甲亢组(P<0.05);超声心动图示,与甲亢组比较,甲亢心非心衰组和甲亢心心衰组患者的RVDd、LVDd、PAP均增加(P<0.05),心输出量(CO)和LVEF均下降(P<0.05),甲亢心心衰组患者RVDd高于甲亢心非心衰组患者(P<0.05);RVDd与PAP和LVDd呈正相关,与SV、CO及LVEF呈负相关。结论甲亢心患者的右心室舒张末期内径值明显增加,发生心衰的甲亢心患者右心室功能下降较左心室功能下降更明显。

Objective To investigate the echocardiographic changes of right ventricular function in the patients with hyperthyroidism heart disease.Methods In this study 79 inpatients with hyperthyroidism heart disease in our hospital were randomly selected as the experimental group and 30 outpatients with hyperthyroidism were selected as the control group.And then the patients in the experimental group were divided into a heart failure group(n=49)and a non-heart failure group(n=30).The general data of the patients were collected;FT3,FT4 and echocardiography were examined in all patients and compared.Results The course of disease was longer,the age of the patients was older and FT3 was significantly higher in the heart failure group than in the control group and the non-heart failure group(P<0.05).Compared with the control group,RVDd,LVDd and PAP were significantly increased but CO and LVEF were significantly decreased in the experimental group(P<0.05).However,RVDd in the heart failure group was significantly higher than that in the non-heart failure group(P<0.05).And RVDd was positively correlated to PAP and LVDd(P<0.05),RVDd was inversely related to SV,CO and LVEF(P<0.05).Conclusions RVDd is increased significantly in the patients with hyperthyroid heart disease,and in the hyperthyroidism patients with heart failure the right ventricular function decreases more significantly than the left ventricular function.