血清胱抑素C、尿微量白蛋白肌酐值测定在老年2型糖尿病早期肾功能损伤中的意义

目的:探究血清胱抑素C(Cys-C)、尿微量白蛋白肌酐值测定(UAlb/Cr)在老年2型糖尿病早期肾功能损伤中的意义。方法:选取我院于2017年4月至2018年5期间收治的老年2型糖尿病早期肾功能损伤患者共70例作为研究组,并选取同期来我院进行健康体检的健康人群70例作为对照组,对比观察2组受检者的血清胱抑素C、尿微量白蛋白肌酐值测定结果。结果:研究组患者的Ccr(56.81±5.94)mL/min低于对照组,Cr(112.61±8.61)mol/L高于对照组,Cys-C(2.94±4.25)mg/L高于对照组,UAlb/Cr比值(158.51±36.55)高于对照组,2组数据比较均具有显著差异,P<0.05,具备统计学意义。结论:Cys-C与UAlb/Cr联合检测在老年2型糖尿病肾病早期检测中具有重要意义,具有较高敏感性,可靠性较高,有利于临床早期诊断、早期干预,可有效延缓、控制终末期肾病的发生。

To explore the significance of serum cystatin C(Cys-C)and urine trace albumin creatinine(UAlb/Cr)in the early renalimpairment of type2diabetes in the elderly.Methods:a total of70patients with early renal impairment of type2diabetes treated in our hospitalfrom April2017to52018were selected as the study group,and70healthy people were selected as the control group in our hospital for healthyphysical examination at the same period.The results of serum Cystin C and urine trace albumin creatinine in the2groups werecompared..Results:the Ccr(56.81+5.94)mL/min of the patients in the study group was lower than the control group,and Cr(112.61+8.61)mol/Lwas higher than the control group.Cys-C(2.94+4.25)mg/L was higher than the control group.The UAlb/Cr ratio(158.51+36.55)was higher thanthe control group.The data of the2groups were all significantly different,P<0.05,with statistical significance.Conclusion:Cys-C and UAlb/Crcombined detection is of great significance in the early detection of type2diabetic nephropathy in the elderly,with high sensitivity andreliability,is conducive to early clinical diagnosis,early intervention,can effectively delay and control the occurrence of end-stage renal disease.