期刊文献+

联合化疗治疗中晚期原发性肝癌的效果观察及研究

下载PDF
导出
摘要 目的:探讨联合化疗治疗中晚期原发性肝癌的效果。方法:于2014年03月--2018年03月收治的45例中晚期原发性肝癌患者为研究对象。化疗方案FOLFOX4治疗23例和XELOX化疗方案治疗22例。以Child-Pugh标准,将肝癌患者分为两组,即A组(Child-PughA级,20例)、B组(Child-PughB级,25例)。结果:两组疾病控制率无差异(p>0.05);A组肝毒性、消化道反应等发生率低于B组,有差异统计学意义(p<0.05)。结论:对于中晚期原发性肝癌患者,联合化疗有利于控制疾病进展,效果显著。但相比于Child-PughB级而言,Child-PughA级中晚期原发性肝癌患者获益更大。
出处 《医学食疗与健康》 2018年第8期49-49,51,共2页 Medical Diet and Health
  • 相关文献

参考文献3

二级参考文献30

  • 1秦叔逵,曹梦苒,钱军,华海清,王琳,何泽明.奥沙利铂为主的FOLFOX方案治疗晚期原发性肝癌[J].临床肿瘤学杂志,2005,10(1):58-60. 被引量:77
  • 2高德荣,韩雅玲,温珍平,冯铁虹,李红,王磊.门冬氨酸钾镁与葡萄糖酸钙联用防治奥沙利铂神经毒性的临床观察[J].现代肿瘤医学,2007,15(3):417-418. 被引量:16
  • 3郝明春,殷学治,王辉,徐莉英,董金华.抗癌药雷替曲塞的合成[J].中国药物化学杂志,2007,17(6):368-371. 被引量:12
  • 4Wei Li,Lin Xu,Ling Zhao,Li Wang,Yong Zhang,Quan Gao,Ling Mai.Cytokine?induced killer cell therapy for advanced pancreatic adenocarcinoma:A case report and review of the literature[J]. Oncology Letters . 2013 (4)
  • 5E.A. Eisenhauer,P. Therasse,J. Bogaerts,L.H. Schwartz,D. Sargent,R. Ford,J. Dancey,S. Arbuck,S. Gwyther,M. Mooney,L. Rubinstein,L. Shankar,L. Dodd,R. Kaplan,D. Lacombe,J. Verweij.New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)[J]. European Journal of Cancer . 2008 (2)
  • 6Shukui Qin,Yuxian Bai,Ho Yeong Lim,Sumitra Thongprasert,Yee Chao,Jia Fan,Tsai-Shen Yang,Vajarabhongsa Bhudhisawasdi,Won Ki Kang,Yu Zhou,Jee Hyun Lee,Yan Sun.Randomized, Multicenter, Open-Label Study of Oxaliplatin Plus Fluorouracil/Leucovorin Versus Doxorubicin As Palliative Chemotherapy in Patients With Advanced Hepatocellular Carcinoma From Asia[J].Journal of Clinical Oncology.2013(28)
  • 7E. Raymond,S. G. Chaney,A. Taamma,E. Cvitkovic&gt.Oxaliplatin: A review of preclinical and clinical studies[J].Annals of Oncology.1998(10)
  • 8Dmitry I. Gabrilovich,Srinivas Nagaraj.Myeloid-derived suppressor cells as regulators of the immune system. Nature Reviews Immunology . 2009
  • 9Shi S,Wang R,Chen Y,et al.Combining antiangiogenic therapy with adoptive cell immunotherapy exerts better antitumor effects in non-small cell lung cancer models. PLoS One . 2013
  • 10Qin SK,Bai Y,Sun Y,et al.Phase III study of oxaliplatin plus5-fluorouracil/leucovorin (FOLFOX 4)versus doxorubicin as pal-liative systemic chemotherapy in advanced HCC in Asian pts. Journal of Clinical Oncology . 2010

共引文献43

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部