美国伊利诺伊大学医学中心临床药师在抗菌药物管理中的工作

Role of Clinical Pharmacists at the University of Illinois Medical Center in Antimicrobial Management

目的探讨美国临床药师在抗菌药物管理中的工作,为我国抗菌药物管理提供借鉴。方法通过作者在美国伊利诺伊大学医学中心6个月的临床药师培训,以临床实践中的案例为例,总结临床药师在抗菌药物治疗中发挥的重要作用以及参与的抗菌药物管理工作。结果美国临床药师在临床实践案例中可开具和调整抗菌药物剂量医嘱、参与对限制级抗菌药物使用的管理,在万古霉素个体化给药、抗菌药物方案调整、给药优化、用药疗程与不良反应监护等方面发挥了重要作用。另外,抗感染临床药师也参与抗菌药物管理计划的工作,如处方的审查、反馈和干预,各类感染抗菌药物用药规范指南的建立与更新,给药优化的干预与数据支持等。结论美国临床药师在抗菌药物管理中的工作对我国抗菌药物管理具有很好的借鉴意义。

Objective To analyze the role of clinical pharmacists in the management of antimicrobial drugs in the United States,and to provide reference for antimicrobial drug management in China.Methods On the basis of the 6 months of clinical pharmacist training at the University of Illinois Medical Center at Chicago,one case was taken as example to analyze the role of clinical pharmacists in the management of antimicrobial drugs.Results In the United States,clinical pharmacists can prescribe initial or adjusted doses,participate in the management of the use of restricted antimicrobial drugs.Clinical pharmacists have played an important role in the individual vancomycin administration,antimicrobial drug regimes adjustment,drug optimization,monitoring adverse effects and treatment duration.In addition,anti-infection clinical pharmacists also participate in antimicrobial stewardship,such as prescription review,feedback and intervention,the establishment and updating of infection and antimicrobial agents guidelines,data support and drug optimization,etc.Conclusion The work of clinical pharmacists in the management of antimicrobial drugs in the United States is a meaningful guidance for our antimicrobial drug management.