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VEGF-A、VEGF-C在宫颈癌侵袭转移中的作用机制研究进展 被引量:18

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摘要 癌细胞直接浸润和淋巴结转移是宫颈癌的重要转移途径。血管内皮生长因子A(VEGF-A)、血管内皮生长因子C(VEGF-C)是血管内皮生长因子家族的重要成员,可参与多种生理病理过程。VEGF-A与其受体特异性结合,刺激肿瘤血管内皮细胞新生而参与宫颈癌的侵袭转移及复发过程;VEGF-C与其受体特异性结合,诱导淋巴管内皮细胞及血管的生成而参与宫颈癌的侵袭转移及复发过程。
出处 《山东医药》 CAS 2018年第35期104-107,共4页 Shandong Medical Journal
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