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磁共振氢质子波谱成像对原发性骨肉瘤的临床应用价值 被引量:2

Clinical value of 1H-magnetic resonance spectroscopy in diagnosis of osteosarcoma
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摘要 目的探讨磁共振氢质子波谱成像(1H-MRS)对原发性骨肉瘤的临床应用价值。方法选取18例临床资料完整并经病理证实的骨肉瘤患者行1H-MRS检查,采用Spectroscopy软件进行分析,得到基线稳定的MRS谱线、Cho及Cho/Cr值。结果高、低度恶性骨肉瘤患者的Cho/Cr值比较,差异有统计学意义(P <0.05)。以Cho/Cr作为诊断指标,最佳诊断界值为Cho/Cr=2.3。结论 1H-MRS可用来评价骨肉瘤的恶性程度。 Objective To explore the clinical value of 1H-magnetic resonance spectroscopy(1H-MRS)in osteosarcoma.Methods Eighteen cases were selected and examined by 1H-MRS scan,which had stable spectral lines,with the measurement parameters of Cho and Cho/Cr ratio.Results Cho/Cr ratio was significantly different between the high-grade and low-grade malignant osteosarcomas.As a diagnostic parameter,the best threshold value of Cho/Cr was 2.3.Conclusions 1H-MRS might be helpful for assessment of malignant degree of osteosarcoma.
作者 李莹 任翠萍 程敬亮 李贝贝 肖翠萍 Ying Li;Cui-ping Ren;Jing-liang Cheng;Bei-bei Li;Cui-ping Xiao(Department of MR,the First Affiliated Hospital of Zhengzhou University,Zhengzhou,Henan 450052,China)
出处 《中国现代医学杂志》 CAS 2018年第29期90-93,共4页 China Journal of Modern Medicine
关键词 骨肉瘤 MRI 磁共振波谱成像 osteosarcoma MRI magnetic resonance spectroscopy
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