负钠透析对维持性血液透析患者体质量及血压的控制效果分析

Analysis on control effect of negative sodium dialysis on body mass and blood pressure in patients with maintenance hemodialysis

目的探讨负钠透析对维持性血液透析患者体质量及血压的控制效果。方法回顾性分析该院门诊2015-2016年60例规律性血液透析患者的临床资料,根据透析液钠浓度不同,分为治疗组(钠浓度135~138mmol/L,n=30)和对照组(钠浓度140mmol/L,n=30),均治疗3个月。观察并比较两组患者血压、心率、体质量等情况。结果治疗组透析后收缩压、舒张压、血清钠浓度均低于透析前及对照组,差异具有统计学意义(P<0.05);治疗组透析过程中的高血压发生次数明显少于对照组,差异有统计学意义[(2.2±0.7)次vs.(9.4±1.5)次,P<0.01];治疗组透析后干体质量明显低于对照组,差异有统计学意义[(63.4±8.2)kg vs.(68.7±10.5)kg,P<0.05]。结论负钠透析能有效控制部分维持性血液透析患者的血压及体质量。

Objective To explore the control effect of negative sodium dialysis on body mass and blood pressure in the patients with maintenance hemodialysis.Methods The clinical data in 60 cases of regular hemodialysis in the outpatient department of this hospital during 2015-2016 were retrospectively analyzed.The patients were divided into the treatment group(sodium concentration 135-138 mmol/L,n=30)and control group(sodium concentration 140 mmol/L,n=30)according to the different concentrations of dialysate sodium.All patients were treated for 3 months.The blood pressure,heart rate,body mass and so on were observed and compared between the two groups.Results The systolic blood pressure,diastolic blood pressure and serum sodium concentration after dialysis in the treatment group were lower than those before dialysis and control group,the difference was statistically significant(P<0.05).The frequency of hypertension during dialysis process in the treatment group was significantly lower than that in the control group,and the difference was statistically significant[(2.2±0.7)times vs.(9.4±1.5)times,P<0.01].After dialysis,the dry body mass of the treatment group was significantly lower than that of the control group,the difference was statistically significant[(63.4±8.2)kg vs.(68.7±10.5)kg,P<0.05].Conclusion Negative sodium dialysis can effectively control blood pressure and body mass in partial maintenance hemodialysis patients.