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干细胞源性外泌体在心血管疾病中的研究进展 被引量:1

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摘要 近年来,干细胞源性外泌体的心脏保护机制已成为研究热点。越来越多的证据表明干细胞能够释放外泌体,其触发分泌依赖于细胞外刺激,如今外泌体的活性成分正在被广泛地研究。既往研究证实,干细胞源性外泌体具有与干细胞相似的心脏保护功能,能促进血管生成,减少细胞凋亡,减少应激带来的损伤。与干细胞相比,外泌体更稳定,较少引起受体细胞的突变以及免疫排斥反应,有望成为治疗心血管疾病的有效方法。本文对干细胞源性外泌体的生物学功能和分子机制进行了综述。
出处 《实用医学杂志》 CAS 北大核心 2018年第18期3143-3145,共3页 The Journal of Practical Medicine
基金 老年创伤性疾病预防诊治创新技术及产品研发项目(项目编号:201508020253)
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