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PARP抑制剂治疗复发性卵巢癌专家共识 被引量:20

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摘要 卵巢癌是最常见的妇科生殖系统肿瘤之一。全球每年新发卵巢癌约23.9万例,死亡15.2万例,占女性恶性肿瘤发生率第7位[1]。根据2015年郝捷院士发表的中国癌症统计数据,我国年新发卵巢癌5.2万余例,死亡2.25万例;发病率年增加6.3%,死亡率年增加21.6%,呈显著上升趋势[2]。患者就诊时多为晚期,5年生存率仅为29%。仅15%患者诊断时为局限期(1期),5年生存率为92%[3]。满意的肿瘤细胞减灭术联合化疗是卵巢癌患者初始治疗选择之一,但晚期患者即使经治疗获得完全缓解,仍有70%~80%出现复发[4]。
出处 《现代妇产科进展》 CSCD 北大核心 2018年第10期721-725,共5页 Progress in Obstetrics and Gynecology
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