摘要
肌少症作为一种在老年人中发病率较高的综合征,日益受到人们的广泛关注,但是目前它的发病机制及治疗措施尚未达成共识。本文围绕维生素D与肌少症的相关性入手,探讨维生素D对于肌肉系统的病理生理作用,维生素D与肌肉细胞生长与衰退的关系,维生素D对肌肉的信号调控及功能的影响。初步阐述了维生素D对于肌少症的影响和作用,对于肌少症的防治提供新的临床思路。
Sarcopenia is a syndrome with high incidence in the elderly people.However,most of its pathogenesis and treatment have not been agreed.This paper focuses on correlation between vitamin D and sarcopenia.The discussion includes pathological and physiological role of vitamin D on bone muscle system,and the growth and degradation of muscle cells with related signal factor.The effect and influence of vitamin D on sarcopenia are discussed,providing a new clinical thinking for the prevention of sarcopenia.
作者
姜宇
宣文华
任天丽
JIANG Yu;XUAN Wenhua;Ren Tianli(Department of Orthopedics,Wuxi Second Hospital Affiliated to Nanjing Medical University,Wuxi 214002,China)
出处
《中国骨质疏松杂志》
CAS
CSCD
北大核心
2018年第9期1246-1249,共4页
Chinese Journal of Osteoporosis
基金
国家自然科学基金资助项目(81602864)