儿童百日咳112例临床特征分析

Analysis on the clinical features of 112 cases of pertussis in children

目的:探讨儿童百日咳的临床特征、诊治及预后。方法:回顾性分析经百日咳鲍特菌PCR确诊为百日咳的112例患儿临床资料,其中未接种百白破联合疫苗57例,接种百白破联合疫苗1次25例,接种百白破联合疫苗2次21例,接种百白破疫苗3次9例。7例患儿有明确家庭百日咳患者接触史。百日咳PCR均阳性。结果:112例患儿均予静脉滴注红霉素,布地奈德雾化吸入等综合治疗,临床治愈104例,好转8例。结论:百日咳是传染性很强的呼吸道疾病,发病率逐年升高。因此,加强对百日咳预防及提高诊治水平,对百日咳防治有重大意义。

Objective:To explore the clinical characteristics,diagnosis,treatment and prognosis of pertussis in children.Methods:The clinical data of 112 children with pertussis diagnosied by bautheria pertussis PCR were analyzed retrospectively.57 cases were not inoculated with pertussis combined vaccine;25 cases were once vaccinated with diphtheria combined vaccine;21 cases of pertusis combined vaccine 2 times;9 cases of pertussis vaccinated 3 times.7 children had a history of family pertussis contact.Pertussis PCR in all those cases were positive.Results:112 children received intravenous drip of erythromycin and nebulized inhalation of budesonide.104 cases were cured and 8 cases improved.Conclusion:Pertussis is a highly contagious respiratory disease,and the incidence is increasing year by year.Therefore,strengthening the prevention and treatment of pertussis has great significance for the prevention and treatment of pertussis.