5例腹膜透析相关的真菌性腹膜炎临床分析

Clinical analysis of fungal infection in peritoneal dialysis patients

目的探讨腹膜透析患者真菌感染的发生率、致病真菌以及感染的主要因素及处理结果。方法回顾性分析58例腹膜透析患者的临床资料,对真菌感染患者从临床症状、真菌学检查、治疗及预后进行详细的论述,探讨腹膜透析与真菌感染的关系。结果腹膜透析治疗的58例患者中有5例发生真菌性腹膜炎,感染率为8.6%,致病菌4例为白念珠菌,1例为近平滑念珠菌,其中4例患者经抗真菌和拔出腹透管处理,治疗效果较为理想。1例患者因病情危重伴有其他细菌感染,最终死于其他并发症。结论真菌感染是腹膜透析患者较严重的并发症,尽管发生率不高,但如果不及时处理后果严重,早诊断、早治疗并根据实际情况考虑拔除腹透管尤为重要。

Objective Peritonitis is one of the most serious complications of peritoneal dialysis.This study analysis the clinical datas of peritoneal dialysis patients with fungal infection,thus reducing the probability of infection and accumulating experience for future treatment.Methods A retrospective analysis of the clinical data of 58 patients treated with peritoneal dialysis was carried out to compare the relationship between peritoneal dialysis and fungal infection and the treatment after infection.Results Among the 58 patients treated by peritoneal dialysis,5 cases had fungal infection,and the infection rate was 8.6%.The therapeutic effect is ideal.Conclusion Fungal infection is one of the most serious complications of peritoneal dialysis patients.Early diagnosis and timely antifungal treatment is important to control the infection.It is particularly important to decide whether to remove the peritoneal dialysis catheter early.