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二甲双胍联合炔雌醇环丙孕酮治疗多囊卵巢综合征的效果 被引量:2

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摘要 目的研究二甲双胍联合炔雌醇环丙孕酮治疗多囊卵巢综合征(PCOS)的临床效果。方法选取2015年5月至2017年4月开封市妇产医院收治的85例PCOS患者作为研究对象,按随机数表法分为对照组(42例)与观察组(43例)。对照组接受炔雌醇环丙孕酮治疗,观察组接受炔雌醇环丙孕酮+二甲双胍治疗,治疗3个月经周期后,比较两组治疗前后血清相关性激素水平及不良反应发生率。结果治疗前,两组LH、T、PRL水平比较,差异无统计学意义(P>0.05);治疗3个月经周期后,观察组LH、T、PRL水平低于对照组,差异有统计学意义(P<0.05)。观察组不良反应发生率[11.63%(5/43)]低于对照组[30.95%(13/42)],差异有统计学意义(P<0.05)。结论对PCOS患者采用二甲双胍联合炔雌醇环丙孕酮治疗,可改善血清相关性激素水平,不良反应发生率较低。
作者 王明辉
出处 《河南医学研究》 CAS 2018年第19期3602-3603,共2页 Henan Medical Research
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