3.0 T MRI 3种扫描序列对颈神经根成像的对比研究

Comparative study on three kinds of MRI sequence for cervical nerve roots with 3.0 T MRI

目的比较3.0 T MRI 3种扫描序列对颈神经根成像的应用价值。材料与方法收集临床需要扫描颈椎MRI患者37例,均行常规序列、三维双回波稳态(three-dimensional double-echo steady state,3D-DESS)序列、多回波数据图像重合(multi-echo data image combination,MEDIC)序列、可变反转角三维快速自旋回波(3D sampling perfection with application optimized contrasts using different flip angle evolutions,3D-SPACE)序列扫描,所有图像均进行后处理重建,对图像质量和正常颈神经根显示、受压颈神经显示清晰度、颈神经根与邻近组织的对比噪声比(contrast noise ratio,CNR)3个方面进行评价。结果 3种扫描序列3个方面两两比较,3D-DESS序列神经根-椎体CNR和神经根-脑脊液CNR均高于MEDIC序列;3D-DESS序列神经根-椎体CNR高于3D-SPACE序列,而3D-DESS序列神经根-脑脊液CNR低于3D-SPACE序列;3D-SPACE序列神经根-脑脊液CNR高于MEDIC序列,3D-SPACE序列神经根-椎体CNR与MEDIC序列差异无统计学意义。图像质量评分3种序列两两对比差异均有统计学意义(P<0.05),3D-DESS序列优于MEDIC序列,而3D-SPACE序列图像质量最差。对受压神经根清晰度的显示,3D-DESS序列和MEDIC序列差异无统计学意义,两序列与3D-SPACE序列对比,差异均有统计学意义(P<0.05),即两序列均优于3D-SPACE序列。结论对于显示神经根结构和诊断神经根病变等方面,3D-DESS序列明显优于MEDIC序列和3D-SPACE序列,对颈神经根成像及颈神经根受压的临床诊断更具优势。

Objective:To compare the applied value of three kinds of MRI sequence for imaging of cervical nerve roots with 3.0 T MRI.Materials and Methods:37 cases need scanning cervical vertebra with 3.0 T MRI were observed,which were performed with conventional MR,three-dimensional double-echo steady state(3D-DESS),multiecho data image combination(MEDIC)and 3D sampling perfection with application optimized contrasts using different flip angle evolutions(3D-SPACE),all of the images were used for postprocessing reconstruction,to evaluate three aspects included image quality and the display of normal cervical nerve roots,the display definition of depressed cervical nerve roots,the contrast noise ratio(CNR)between cervical nerve roots and adjacent tissue.Results:Three kinds of MRI sequence were compared in pairs in three aspects,MR 3D-DESS exceeds MR MEDIC in both CNR of nerve root-vertebra and CNR of nerve root-cerebrospinal fluid.MR 3D-DESS exceeds MR 3D-SPACE in CNR of nerve root-vertebra,but MR 3D-SPACE exceeds MR 3D-DESS in CNR of nerve root-cerebrospinal fluid.MR 3D-SPACE exceeds MR MEDIC in CNR of nerve root-cerebrospinal fluid,but no statistical difference between MR 3D-SPACE and MR MEDIC in CNR of nerve root-vertebra.There were statistical differences for three kinds of MRI sequence were compared in pairs in three aspects of image quality,the MR 3D-DESS superior to the MR MEDIC,the image quality of MR 3D-SPACE was worst.For the display definition of depressed cervical nerve roots,there was no statistical difference between MR 3D-DESS and MR MEDIC,which compared with MR 3D-SPACE,they superior to MR 3D-SPACE,they were statistical difference.Conclusions:MR 3D-DESS significantly outperformed the MR MEDIC and MR 3D-SPACE in aspects of showing the structure of nerve roots and diagnosing the compression of nerve roots,and same time,MR 3D-DESS had advantage in imaging of cervical nerve roots and clinical diagnosis of cervical nerve roots injury.