小儿鼠伤寒沙门菌感染临床分析77例

Clinical analysis of 77 cases of salmonella typhimurium infection in children

目的:回顾分析临床儿童鼠伤寒沙门菌感染的情况,指导临床减少感染率,并合理用药。方法:分析77例感染鼠伤寒沙门菌患儿的年龄、季节,通过对患儿粪便进行细菌培养、分离,并对分离出的鼠伤寒沙门菌进行药物敏感性鉴定。结果:本地区感染鼠伤寒沙门菌的77例患儿<1岁最多(76.6%),以6、7、8、9、10月发病率较高。根据敏感试验结果,鼠伤寒沙门菌对多种抗生素出现不同程度的耐药性,敏感的药物由高到低依次为亚胺培南、头孢他啶、头孢吡肟、哌拉西林、氨曲南等。结论:鼠伤寒沙门菌对多种抗生素产生耐药性,临床上需根据药敏结果合理使用抗生素。

Objective:To make a retrospective analysis of clinical children with salmonella typhimurium infection,guide the clinical reduction of infection rate,and rational use of drugs.Methods:The age and season of 77 children with salmonella typhimurium were analyzed.The bacteria were cultured and isolated from the feces of the children,and the drug sensitivity of salmonella typhimurium was determined.Results:77 cases of salmonella typhimurium in the region were the most children under 1 years old(76.6%).In June,July,August,September,October,the incidence was higher.According to the results of sensitivity test,salmonella typhimurium was resistant to a variety of antibiotics in varying degrees,the sensitive drugs from high to low were imipenem,ceftazidime,cefepime,piperacillin,aztreonam,and so on.Conclusion:Salmonella typhimurium is resistant to many kinds of antibiotics.It is necessary to use antibiotics rationally according to the results of antibiotic susceptibility.