替吉奥联合奥沙利铂治疗晚期胃癌45例的临床分析

Clinical analysis of 45 patients with advanced gastric cancer treated with Ti Ji Ao

目的:探讨替吉奥治疗晚期胃癌患者的效果及安全性。方法:收治晚期胃癌患者90例,分为对照组和观察组。观察组采用替吉奥联合奥沙利铂治疗,对照组采用FOLFOX4方案治疗,比较两组治疗效果。结果:观察组总有效率,以及0.5年、1年、2年生存率均显著高于对照(P<0.05)。观察组不良反应发生率显著低于对照组(P<0.05)。结论:替吉奥治疗晚期胃癌患者的临床疗效显著,能明显延长患者生存期,且药物不良反应少。

Objective:To explore the effect and safety of Ti Ji Ao in the treatment of patients with advanced gastric cancer.Methods:90 patients with advanced gastric cancer were selected,they were divided into the control group and the observation group.The observation group was treated with Ti Ji Ao and oxaliplatin,the control group was treated with FOLFOX4,we compared the therapeutic effects of the two groups.Results:In the observation group,the total effective rate,the survival rate of half a year,1 year and 2 years were all significantly higher than those of the control group(P<0.05).The incidence of adverse reactions in the observation group was significantly lower than that in the control group(P<0.05).Conclusion:The effect of Ti Ji Ao in the treatment of patients with advanced gastric cancer was significant,it can obviously prolong the survival time of patients,and the side effects were few.