急性缺血性卒中病人mRS评分与中医证型的相关性研究

Correlation between mRS score and Traditional Chinese Medicine Syndromes in Patients with Acute Ischemic Stroke

目的探讨急性缺血性卒中临床预后与中医证型的相关性。方法入组病例共200例,对不同证型病人进行发病时、发病后14d、30d、90d的改良Rankin量表(mRS)评分。结果风中脑络-瘀血型、风中脏腑-阳闭型mRS评分:14d较0d、30d较14d及90d较30d比较差异均有统计学意义(P <0.01);风中脑络-阴虚型mRS评分:14d较0d及30d较14d比较差异均有统计学意(义P <0.05);风中脏腑-脱证型mRS评分:14d较0d、30d较14d及90d较30d比较均无统计学意义(P>0.05)。结论不同中医证型病人mRS评分在不同时间点有明显差异;分辨中医证型有助于对急性缺血性卒中临床预后的判断。

Objective To investigate the correlation between clinical prognosis and traditional Chinese medicine(TCM)syndromes in patients with acute ischemic stroke.Methods Two hundreds patients with acute ischemic stroke were enrolled in the study.The modified Rankin Scale(mRS)scores were evaluated at 0 day(0 d),14 days(14 d),30 days(30 d),and 90 days(90 d)after onset in patients with different TCM syndromes.Results There were significant differences in the mRS scores between the 14 d and 0 d,or the 14 d and 30 d,or the 90 d and 30 d in blood stasis syndrome of stroke involving meridians collaterals and yang dysuria syndrome of stroke involving Zang fu organs(P<0.01).There were significant differences in the mRS scores between the 14 d and 0 d,or the 14 d and 30 d in yin deficiency syndrome of stroke involving meridians collaterals(P<0.01).There was no differences in the mRS scores between the 14 d and 0 d,or the 14 d and 30 d,or the 90 d and 30 d in desertion disease syndrome of stroke involving Zang fu organs(P>0.05).Conclusion The mRS scores in patients with different TCM syndromes were significantly different at different time points.TCM syndromes help to determine the clinical prognosis of acute ischemic stroke.