沙丁胺醇联合布地奈德氧气雾化吸入治疗支气管哮喘急性发作的效果分析

Effect analysis of Salbutamol combined with Budesonide for oxygen atomization inhalation in the treatment of acute attack of bronchial asthma

目的对支气管哮喘急性发作的患者采用沙丁胺醇联合布地奈德雾化吸入治疗的效果进行分析。方法 800例支气管哮喘急性发作患者,随机分为对照组和观察组,每组400例。两组患者入院后均进行基础性的抗感染以及止咳治疗,在此基础上,对照组患者采用吸氧治疗,观察组患者采用沙丁胺醇联合布地奈德氧气雾化吸入治疗,比较两组患者临床疗效及肺功能指标。结果观察组患者治疗总有效率为100%,显著高于对照组的75%,差异具有统计学意义(P<0.05)。治疗后,观察组患者用力肺活量(FVC)为(2.6±0.4)L、呼气峰值流速(PEF)为(2.8±0.6)L/s、第1秒用力呼气容积(FEV1)为(2.0±0.3)L,均高于对照组的(2.2±0.3)L、(2.5±0.2)L/s、(1.8±0.1)L,差异具有统计学意义(P<0.05)。结论采用沙丁胺醇联合布地奈德雾化吸入治疗支气管哮喘急性发作患者,能够显著改善患者的肺功能情况,提高临床疗效,值得在临床推广应用。

Objective To analyze the therapeutic effect of Salbutamol combined with Budesonide for oxygen atomization inhalation in the treatment of acute attack of bronchial asthma.Methods A total of 800 patients with acute attack of bronchial asthma were randomly divided into control group and observation group,400 cases in each group.Patients in the two groups received basic anti infection and antitussive therapy after admission.On this basis,patients in the control group were given oxygen treatment,patients in the observation group were given Salbutamol combined with Budesonide for oxygen atomization inhalation.The clinical efficacy and pulmonary function indexes between the two groups were compared.Results The total effective rate of the observation group was 100%,which was significantly higher than 75%of the control group,the difference was statistically significant(P<0.05).After treatment,the forced vital capacity(FVC),peak expiratory flow(PEF)and forced expiratory volume in 1st second(FEV1)of the observation group were(2.6±0.4)L,(2.8±0.6)L/s and(2.0±0.3)L respectively,which were significantly higher than(2.2±0.3)L,(2.5±0.2)L/s and(1.8±0.1)L of the control group,the differences were statistically significant(P<0.05).Conclusion The application of Salbutamol combined with Budesonide for oxygen atomization inhalation in the treatment of acute attack of bronchial asthma can significantly improve the pulmonary function of patients and improve their clinical efficacy,it is worthy of clinical promotion and application.