胃癌卵巢转移的新近诊疗进展

Recent progress in diagnosis and treatment of ovarian metastasis of gastric cancer

胃癌是我国常见的恶性肿瘤,给我国造成了严重的疾病负担。胃癌可以发生卵巢转移,多见于43～48岁的绝经前女性。目前认为胃癌通过淋巴道转移的可能性更大,大多累及双侧卵巢,术中探查时发现的腹膜转移率很高,患者预后较差。诊断时需要结合胃癌病理及双侧卵巢肿瘤的影像学表现。目前治疗方法尚有争议,对术前评估可切除的单纯卵巢转移患者行根治性或者最大程度的减瘤手术,术后加以全身化疗及腹腔热灌注化疗可以提高总生存期。目前仍然需要更多大规模的研究数据进一步探讨有效的治疗方案。

Gastric cancer is a common malignancy in China,causing a heavy disease burden.Ovarian metastasis of gastric origin is mostly encountered in premenopausal women aged 43-48 years.At present,ovarian metastasis of gastric origin results more likely from lymphatic metastasis.Most of the cases involve bilateral ovaries.The peritoneal metastasis rate detected during intraoperative exploration is high,and the prognosis of these patients is poor.The diagnosis requires the combination of gastric cancer pathology and imaging features of bilateral ovarian tumors.The current treatment methods are still controversial.Patients with resectable isolated ovarian metastasis undergoing radical or maximally cytoreductive surgery with postoperative chemotherapy and hyperthermic intraperitoneal chemotherapy may have longer overall survival.There is still a need for more large-scale research data to further explore effective treatment options.