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低剂量阿奇霉素与噻托溴铵治疗支气管扩张 被引量:3

Clinical Analysis of Low-dose Azithromycin and Tiotropium Bromide in the Treatment of Bronchiectasis
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摘要 目的探讨噻托溴铵粉雾剂联合低剂量阿奇霉素治疗支气管扩张的临床效果。方法随机将我院2016年6月—2017年6月收治的86例支气管扩张患者分为两组,每组43例。两组均行常规治疗,对照组行噻托溴铵粉治疗,观察组在对照组的基础上行低剂量阿奇霉素治疗。比较两组临床疗效。结果观察组急性发作频次、肺功能指标、咳痰量变化以及CRP水平等指标均优于对照组(P <0.05)。结论噻托溴铵联合低剂量阿奇霉素可以增强患者的肺功能,并降低急性发作频次。 Objective To investigate the clinical effect of tiotropium bromide powder combined with low-dose azithromycin in the treatment of bronchiectasis.Methods Eighty-six patients with bronchiectasis admitted to our hospital from June 2016 to June 2017 were randomly divided into two groups,43 cases in each group.Routine treatment was performed in both groups,and the control group was treated with tiotropium bromide powder.The observation group was treated with low-dose azithromycin on the basis of the control group.The clinical efficacy of the two groups was compared.Results The frequency of acute attack,lung function index,cough volume and CRP level in the observation group were significantly better than the control group(P<0.05).Conclusion Tiotropium bromide combined with low-dose azithromycin can significantly enhance the lung function of patients and reduce the frequency of acute attacks.
作者 郑洪飞 ZHENG Hongfei(Department of Respiratory and Critical Care Medicine,Chengde Medical College Affiliated Hospital,Chengde Hebei 067000,China)
出处 《中国卫生标准管理》 2018年第20期80-82,共3页 China Health Standard Management
关键词 噻托溴铵 阿奇霉素 支气管扩张 肺功能 急性发作频次 临床疗效 tiotropium bromide azithromycin bronchiectasis pulmonary function frequency of acute attacks clinical efficacy
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