H-UPPP术后镇痛方式的选择及临床效果观察

The Selection of Analgesic Method after H-UPPP and Its Clinical Effect Observation

目的:探讨改良悬雍垂腭咽成形术(H-UPPP)的术后镇痛方式的选择及临床效果观察。方法:选取本院收治的进行H-UPPP手术的患者93例,按照随机数字表法将其分为帕瑞昔布钠组(术后肌内注射帕瑞昔布钠镇痛)、曲马多组(术后肌内注射曲马多镇痛)和空白对照组(不采用任何镇痛措施),各31例。比较三组术后疼痛程度(VAS)以及不良反应发生情况。结果:术后12、24、36、48、72 h,帕瑞昔布钠组和曲马多组VAS评分均低于空白对照组,帕瑞昔布钠组VAS评分均低于曲马多组,比较差异均有统计学意义(P<0.05);曲马多组不良反应发生率高于空白对照组、帕瑞昔布钠组(P<0.05),空白对照组、帕瑞昔布钠组不良反应发生率比较差异无统计学意义(P>0.05)。结论:帕瑞昔布钠更适合应用于H-UPPP术,镇痛效果明显且不良反应少,值得临床推广使用。

Objective:To investigate the choice and clinical effect of analgesia after H-UPPP.Method:A total of 93 patients who underwent H-UPPP in our hospital were selected,according to the random number table method,they were divided into Paracoxib Sodium group(postoperative intramuscular injection of Parecoxib Sodium analgesia),Tramadol group(postoperative intramuscular injection of Tramadol analgesia)and blank control group(no pain relief measures),31 cases in each group.The postoperative pain(VAS)and adverse reactions were compared among the three groups.Result:At 12,24,36,48 and 72 hours after operation,the VAS scores of Paracoxib Sodium group and Tramadol group were lower than those of blank control group,and the VAS scores of Paracoxib Sodium group were lower than those of Tramadol group,the differences were statistically significant(P<0.05).The incidence of adverse reactions in Tramadol group was higher than those of blank control group and Paracoxib Sodium group(P<0.05),but the blank control group and Paracoxib Sodium group was compared,the difference was not statistically significant(P>0.05).Conclusion:Paracoxib Sodium is more suitable for the application of H-UPPP,the analgesic effect is obvious and less adverse reactions,worthy of clinical application.