益母草注射液对剖宫产产妇产后恢复、子宫复旧与氧化损伤修复的影响研究

Study on the Influence of Leonurus Heterophyllus Injection for the Postpartum Recovery,Uterine Involution and Oxidative Damage Repair of Delivery Women with Cesarean Section

目的:研究与分析益母草注射液对剖宫产产妇产后恢复、子宫复旧与氧化损伤修复的影响。方法:选取2017年1月-2018年1月本院收治的90例剖宫产产妇。按照随机数字表法将其分为观察组和对照组,各45例。对照组采用缩宫素治疗,观察组在对照组基础上加用益母草注射液。比较两组产后不同时间的出血量、子宫体积、宫底下降高度、血红蛋白水平、恶露消失时间及治疗前后的氧化应激指标表达水平。结果:产后不同时间,观察组出血量均少于对照组,子宫体积均小于对照组,宫底下降高度均优于对照组,血红蛋白水平均高于对照组,恶露消失时间短于对照组,比较差异均有统计学意义(P<0.05);治疗前,两组氧化应激指标表达水平比较差异无统计学意义(P>0.05),治疗后,观察组氧化应激指标表达水平均优于对照组(P<0.05)。结论:益母草注射液对剖宫产产妇产后恢复、子宫复旧与氧化损伤修复的影响较好,在剖宫产产妇中具有较高的应用价值。

Objective:To study and analyze the influence of Leonurus Heterophyllus Injection for the postpartum recovery,uterine involution and oxidative damage repair of delivery women with cesarean section.Method:A total of 90 delivery women with cesarean section in our hospital from January 2017 to January 2018 were selected.According to the random number table method,they were divided into observation group and control group,45 cases in each group.The control group was treated with Oxytocin,while observation group was given Leonurus Heterophyllus Injection on the basis of control group.The amount of postpartum hemorrhage,uterine volume,fundus descent height,hemoglobin level,lochia disappearance time and the level of oxidative stress before and after treatment between two groups were compared.Result:At different postpartum time,the amount of bleeding in observation group were less than those of control group,the uterine volume were less than those of control group,the fundus descent height were better than those of control group,the level of hemoglobin were higher than those of control group,and lochia disappearance time was shorter than that of control group,the differences were statistically significant(P<0.05).Before treatment,the expression level of oxidative stress markers in two groups was compared,the difference was not statistically significant(P>0.05),after treatment,the expression level of oxidative stress in observation group was better than that of control group(P<0.05).Conclusion:The influence of Leonurus Heterophyllus Injection for the postpartum recovery,uterine involution and oxidative damage repair of delivery women with cesarean section are better,and it has higher application value in the delivery women with cesarean section.