三维功率多普勒超声评价重度子痫前期孕妇肾脏血流灌注

Evaluation of renal perfusion in pregnant women with severe preeclampsia by three-dimensional power Doppler ultrasound

目的探讨三维功率多普勒超声(3D-PDUS)评估重度子痫前期孕妇肾脏血流灌注的价值。方法选择2016年6月至2017年8月在江阴市人民医院确诊的重度子痫前期孕妇34例(观察组)及正常妊娠孕妇36例(对照组),应用三维功率多普勒超声及虚拟器官计算机辅助分析(VOCAL)技术,分别测量并比较两组孕妇3项肾脏血流灌注参数:血管指数(VI)、血管化血流指数(VFI)及血流指数(FI)。结果观察组34例重度子痫前期孕妇与对照组正常妊娠孕妇肾脏血流灌注参数VI测值比较[(48.211±7.369)%vs (60.751±5.893)%]差异有统计学意义(t=7.835,P <0.01);且两组孕妇肾脏血流灌注参数VFI测值比较(11.753±1.743 vs 16.273±2.749)差异亦有统计学意义(t=8.264,P <0.01);表明重度子痫前期孕妇肾脏血流灌注量较少;而观察组与对照组孕妇肾脏血流灌注参数FI测值比较差异无统计学意义。结论 3D-PDUS技术对评估重度子痫前期孕妇肾脏血流灌注状况有重要诊断价值。

Objective To investigate the value of three-dimensional power Doppler ultrasound(3D-PDUS)in estimating renal perfusion in pregnant women with severe preeclampsia.Methods From June 2016 to August 2017,3D-PDUS and Virtual Organ Computer-aided Analysis(VOCAL)technique were applied in 34 pregnant women with severe preeclampsia(observation group)and 36 normal pregnant women(control group)in Jiangyin people's Hospital.Parameters for renal perfusion,including vascular index(VI),vascularization flow index(VFI)and blood flow index(FI),were calculated and compared between the two groups.Results Both VI[(48.211±7.369)%vs(60.751±5.893)%,t=7.835,P<0.01]and VFI(11.753±1.743 vs 16.273±2.749,t=8.264,P<0.01)showed statistically significant difference between severe preeclampsia group and control group.The results indicated that renal perfusion decreased in severe preeclampsia.There was no statistically significant difference for FI between the observation group and the normal group.Conclusion 3D-PDUS technique plays an important role in evaluating renal perfusion in pregnant women with severe preeclampsia.