急性心肌梗死后室性心律失常应用胺碘酮治疗临床探讨

Clinical study of amiodarone in the treatment of ventricular arrhythmia after acute myocardial infarction

目的:探讨急性心肌梗死后室性心律失常实施胺碘酮治疗的临床疗效。方法:收治急性心肌梗死后室性心律失常患者77例,随机分成常规组和治疗组。常规组采用利多卡因治疗,治疗组采用胺碘酮治疗,比较两组治疗效果。结果:两组治疗后左室射血分数(LVEF)、左室短轴缩短率(FS)、左室快速充盈期及左房收缩期二尖瓣血流速度(E/A)及显效率差异有统计学意义(P<0.05)。两组不良反应发生率差异无统计学意义(P>0.05)。结论:急性心肌梗死后室性心律失常实施胺碘酮治疗的临床疗效显著。

Objective:To explore the clinical effect of amiodarone in the treatment of ventricular arrhythmia after acute myocardial infarction.Methods:77 patients with ventricular arrhythmia after acute myocardial infarction were selected,they were randomly divided into the routine group and the treatment group.The routine group was treated with lidocaine,and the treatment group was treated with amiodarone,we compared the therapeutic effect of the two groups.Results:After treatment,there were significant differences in the left ventricular ejection fraction(LVEF),the short axis shortening rate of left ventricle(FS),the mitral flow velocity(E/A)of fast filling period of left ventricle and left atrial systolic phase and marked improvement rate in the two groups(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:The clinical effect of amiodarone in the treatment of ventricular arrhythmia after acute myocardial infarction was significant.