摘要
CD26是T细胞表面的活化抗原及共刺激分子,参与T细胞成熟活化以及发挥免疫效应的全过程。在人体诸多相关免疫性疾病,包括自身免疫性疾病、炎性感染性疾病、肿瘤等疾病中,CD26通过参与T细胞的免疫调节发挥不可或缺的作用。
CD26,as a T cell surface antigen and a costimulatory molecule,is involved in the whole process of T cell maturation,activation and the realization of immune effect.In many immune diseases of human,including autoimmune diseases,inflammatory diseases,cancer and so on,CD26 plays an indispensable role through the immune regulation of T cells.
作者
朱怡
杨晓清
张玉泉
ZHU Yi;YANG Xiao-qing;ZHANG Yu-quan(Medical College of Nantong University,Nantong 226001;Dept.of Obstetrics and Gynecology,the Affiliated Hospital of Nantong University,Nantong 226001,China)
出处
《基础医学与临床》
CSCD
2018年第11期1635-1639,共5页
Basic and Clinical Medicine
基金
南通大学研究生科技创新计划项目(YKC15003)
江苏省青年医学重点人才项目(QNRC2016704)
关键词
CD26
二肽酶Ⅳ
T细胞
免疫调节
CD26
dipeptidyl peptidaseⅣ(DPPⅣ)
T cell
immune regulation
