超敏C反应蛋白与急性脑梗死的相关性研究

Study of correlation between C-reaction protein and acute cerebral infarction

目的:通过分析患者的超敏C反应蛋白(C-Reactive protein,hs-CRP)检测结果,研究hs-CRP与急性脑梗死之间的联系。方法:随机筛选2014年至2017年我院确诊的79例急性脑梗死患者为观察组,另外,随机选取体检健康者56例为对照者,观察组和对照组都进行hs-CRP检测,对两组hs-CRP检测结果进行数据分析。结果:急性脑梗死组中hs-CRP浓度比对照组普遍偏高,差异有统计学意义(P <0. 05);缺血性脑血管复发组hs-CRP浓度明显高于首发组,差异有统计学意义(P <0. 05);中、大型病灶组hs-CRP浓度明显高于小病灶组,差异有统计学意义(P <0. 05);中、重度急性脑梗死患者hs-CRP浓度均高于微小型患者组,差异有统计学意义(P <0. 05);死亡组hs-CRP浓度明显比恢复组更高,差异有统计学意义(P <0. 05)。结论:机体hs-CRP浓度和急性脑梗死相关,临床可根据hs-CRP的浓度诊断急性脑梗死患者的脑梗严重程度及病灶分型,并且也能为脑梗死患者的预后评估提供参考指标,降低急性缺血性脑梗死死亡率,提高急性缺血性脑梗死阳性检出率。

Objective The relationship between hypersensitivity C-reactive protein(C-reactive protein,hs-CRP)and the acute cerebral infarction was studied by analyzing the detection results of patients hs-CRP.Methods Selected 79 patients with acute cerebral infarction as observation group during 2014 to 2017,and 56 healthy people as contrast group.The observation group and the contrast group take on the hs-CRP detection,then analyse the detection results of two groups of income.Results The hs-CRP concentration in the acute cerebral infarction group was generally higher than the contrast group(P<0.05).In addition,among the patients with acute cerebral infarction,the hs-CRP concentration of the recurrent group about ischemic cerebral vessels was significantly higher than that of the first group(P<0.05).According to the comparison of cerebral infarction degree,it was found that the hs-CRP concentration in the middle and huge lesion groups was significantly higher than that in the small lesion groups(P<0.05).In the most obvious is that a group of patients with severe acute cerebral infarction,their hs-CRP concentration was higher than in patients with small group(P<0.05),it is also a direction of follow-up study.Conclusion The hs-CRP concentration is associated with acute cerebral infarction,related to diagnosis the acute cerebral infarction and focal points.Also can offer reference for the prognosis of patients with cerebral infarction assessment indicators,reduce the mortality of ischemic cerebral infarction,improve the positive detection rate of acute ischemic cerebral infarction.