单侧甲状腺切除术后甲状腺激素水平的临床评价

Clinical evaluation of thyroid hormone level after unilateral thyroidectomy

目的:探讨单侧甲状腺切除术后甲状腺激素水平的变化。方法:收治甲状腺疾病患者100例,均给予单侧甲状腺切除术治疗。年龄>60岁患者作为老年组,年龄≤60岁患者作为中青年组,比较两组术前、术后1个月、术后2个月、术后3个月、术后6个月以及术后12个月促甲状腺激素水平(TSH)、游离三碘甲状腺原氨酸水平(FT3),以及游离甲状腺素水平(FT4)。结果:老年组术后1个月～术后6个月TSH升高,高于术前及中青年组,差异有统计学意义(P<0.05)。老年组术后1个月～术后1年FT3、FT4下降,低于术前及中青年组,差异有统计学意义(P<0.05)。结论:中青年组单侧甲状腺切除术后甲状腺激素水平的变化不大,而年龄>60岁的患者术后容易出现甲状腺功能减退。

Objective:To investigate the change of thyroid hormone level after unilateral thyroidectomy.Methods:100 cases of patients with thyroid diseases were treated by unilateral thyroidectomy.The patients above 60 years old were as the old-aged group,the patients below 60 years old as the middle-young-aged group,the thyroid stimulating hormone(TSH)levels,free triiodothyronine(FT3),and free tetraiodothyronine(FT4)level before operation,one month after operation,two months after operation,three months after operation,six months after operation and 12 months after operation were compared between the two groups.Results:The TSH in the old-aged group increased from one month to six months after operation,which was higher than before operation and that in the middle-young-aged group,and the difference was statistically significant(P<0.05).The FT3 and FT4 in the old-aged group decreased from one month to one year after operation,which was lower than before operation and that in the middle-young-aged group,and the difference was statistically significant(P<0.05).Conclusion:The level of thyroid hormone in middle-young-aged patients after unilateral thyroidectomy had little change,but the patients older than 60 years old were prone to hypothyroidism.