血清糖类抗原CA-199、CA-125对诊断肺癌、肝癌的临床价值

Clinical value of serum carbohydrate antigen CA-199 and CA-125 in the diagnosis of lung cancer and liver cancer

目的:分析血清糖类抗原CA-199、CA-125对诊断肺癌、肝癌的临床价值。方法:收治肺癌患者、肝癌患者以及健康体检患者各40例,检测血清中CA-199和CA-125的含量。结果:肺癌组患者CA-199平均水平(54.64±6.04)、CA-125水平(126.48±17.45),肝癌组患者CA-199平均水平(50.04±6.82)、CA-125水平(136.47±24.8),健康组患者CA-199平均水平(17.32±1.15)、CA-125水平(12.42±0.64)。健康体检者与肺癌组患者、肝癌组患者检查指标差异有统计学意义(P<0.05)。结论:血清糖类抗原CA-199、CA-125含量在肺癌诊断与肝癌诊断工作中具有较高的临床应用价值,但不能作为鉴别肝癌与肺癌的标准。

Objective:To analyze the clinical value of serum carbohydrate antigen CA-199 and CA-125 in the diagnosis of lung cancer and liver cancer.Methods:The serum levels of CA-199 and CA-125 were detected in 40 patients with lung cancer,40 patients with liver cancer and 40 patients with physical examination.Results:The average level of CA-199 was(54.64±6.04)and CA-125 level was(126.48±17.45)in patients with lung cancer,the average level of CA-199 in the HCC group was(50.04±6.82)and CA-125 level was(136.47±24.8),the average level of CA-199 in the healthy group was(17.32±1.15)and the CA-125 level was(12.42±0.64).There was significant difference between the patients in the health examination group and those in the lung cancer group and the liver cancer group(P<0.05).Conclusion:The levels of serum carbohydrate antigens CA-199 and CA-125 have high clinical value in the diagnosis of lung cancer and liver cancer,but they can not be used as the criteria for differentiating liver cancer from lung cancer.