区域选择性合成二苯并[d,f][1,3]二噁烷

Regioselective Synthesis of Dibenzo [d,f][1,3] dioxepines

针对二苯并[d,f][1,3]二噁烷传统制备方法中易产生二羟基联苯乙烯副产物的缺点,本文以路易斯酸性胍盐离子液体为催化剂,2,2'-二羟基联苯和端基炔为原料,高区域选择性的合成了二苯并[d,f][1,3]二噁烷,收率39%～84%。本方法适用于各种端基炔。路易斯酸性胍盐离子液体循环利用5次,活性不变。

In order to overcome the shortcomings of facile production of dihydroxy diphenyl ethylene by-product in traditional method,dibenzo[d,f][1,3]dioxepines was synthesized highly regioselectively from a broad range of terminal alkynes with Lewis acidic guanidinium ionic liquid catalyst in 39%~84%yields.The Lewis acidic guanidinium ionic liquid can be reused five times without significantly decrease in catalytic activity.