糖尿病心肌病影像诊断研究进展

Research progress in imaging diagnosis of diabetic cardiomyopathy

糖尿病心肌病(diabetic cardiomyopathy,DCM)可导致糖尿病患者心力衰竭甚至死亡,是糖尿病的一种严重的并发症。早期表现为能量代谢、心肌脂肪变性、微循环灌注异常等,逐步发展为心肌细胞重塑、心功能异常和心肌纤维化等。DCM起病隐匿,致病分子机制尚未完全阐明,诊断标准不明确。目前可通过一些影像学检查间接检测心肌细胞可能存在的病理改变,做出诊断,及时干预,并监测病情发展,逆转或延缓病情,改善预后。本文就DCM病程中不同阶段的影像检测方法进行相关综述。

Diabetic cardiomyopathy(DCM)can lead to heart failure or even death in diabetic patients,which is a serious complication of diabetes mellitus.The early manifestations of DCM include abnormal energy metabolism,myocardial steatosis,abnormal microcirculation perfusion,etc.And might gradually develop into myocardial cell remodeling,cardiac dysfunction,and myocardial fibrosis.The pathogenesis of DCM has not been fully elucidated.The diagnostic criteria are unclear.At present,we can indirectly detect the possible pathological changes of cardiomyocytes with the help of imaging examinations,therefore to make a diagnosis,intervene in time,monitor the development of the disease,reverse or delay the condition,and improve the prognosis.In this paper,the imaging detection methods in different stages of DCM are reviewed.