杨桃不同部位提取物抑制α-葡萄糖苷酶的作用

α-Glucosidase Inhibitory Activities of the Extracts from Different Parts of Averrhoa Carambola

目的:比较杨桃根、叶和果实三个部位不同极性溶剂提取物对α-葡萄糖苷酶的抑制作用。方法:建立高效液相色谱法测定体外抑制α-葡萄糖苷酶作用,对杨桃不同部位提取物的抑制作用进行评价筛选。结果:同等质量浓度下,杨桃根各提取物均对α-葡萄糖苷酶有抑制作用,杨桃叶乙醇冷浸提取物的抑制活性较强,而杨桃果实各提取物对α-葡萄糖苷酶抑制作用较差。结论:杨桃根各提取物对α-葡萄糖苷酶均有较强抑制作用,其作为α-葡萄糖苷酶抑制剂具有潜在开发价值。

Objectives:To studyα-glucosidase inhibitory activities of the extracts from the roots,leaves and fruits part of Averrhoa carambola using different polar solvent.Methods:By establishing high-performance liquid chromatography method to evaluateα-glucosidase inhibitory activities in vitro,the activities of the extracts from different parts of Averrhoa carambola were screened.Results:All of the extracts from the root part of Averrhoa carambola showed inhibitory activities againstα-glucosidase.The ethanol extracts obtained under room temperature showed stronger inhibitory activities ofα-glucosidase.The extracts from fruit part showed very weak inhibitory activities againstα-glucosidase.Conclusions:All of the extracts from the root part of Averrhoa carambola showed inhibitory activities againstα-glucosidase,which showed a potent value to develop asα-glucosidase inhibitors.