冠状动脉血流储备在冠状动脉微血管病变中的应用进展

Progresses of coronary flow reserve in coronary microvascular disease

冠状动脉微血管病变(CMVD)普遍存在于无梗阻性冠状动脉疾病的胸痛患者中,并与不良心血管预后相关。测定冠状动脉血流储备(CFR)是评价CMVD的有效方法之一。临床上可通过多种有创或无创性检查方法定量测定CFR,对早期诊断CMVD、预后评估及制定临床治疗方案等均有重要价值。本文就CFR在CMVD中的应用进展进行综述。

Coronary microvascular disease(CMVD)is prevalent in patients with chest pain of unobstructed coronary artery disease,which is associated with adverse cardiovascular events.Measurement of coronary flow reserve(CFR)is one of the effective methods for evaluating CMVD.CFR can be quantified with a variety of methods,including invasive techniques and noninvasive techniques,which have important clinical value for early diagnosis,prognosis assessment and clinical treatment of CMVD.The research progresses of CFR in CMVD were reviewed in this article.