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雷迪帕韦-索非布韦治疗丙型病毒性肝炎(丙肝)肝硬化的临床效果探析 被引量:2

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摘要 目的探究雷迪帕韦-索非布韦治疗丙型病毒性肝炎(丙肝)肝硬化的临床效果。方法选取我院于2016年3月至2017年5月接收的120例患者,根据患者病情等级来划分,分为肝硬化失代偿期、肝硬化代偿期两组,两组患者均进行雷迪帕韦-索非布韦治疗,对比观察两组患者的疗效。结果本次研究结果显示,将雷迪帕韦索非布韦应用到丙型病毒型肝硬化患者的治疗中,肝硬化失代偿期组与肝硬化代偿期组两组患者HCV-RNA转阴率均无较大的差别;肝硬化失代偿期组的不良反应发生率为4.41%,肝硬化代偿期组患者的不良反应发生率为3.84%;两组患者的HCV-RNA转阴率、不良反应发生率对比差异不明显,P> 0.05,无统计学意义。肝硬化失代偿期患者的PCⅢ、HA水平明显比肝硬化代偿期组患者PCⅢ、HA水平低很多,对比差异显著,P <0.05,有统计学意义。结论雷迪帕韦-索非布韦治疗丙型病毒性肝炎肝硬化的临床效果显著,值得推广。
作者 闵广艳
出处 《中国医药指南》 2018年第31期42-42,共1页 Guide of China Medicine
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