颅骨修补术后癫痫发作的危险因素分析

Risk factors of epileptic seizures after cranioplasty

目的探讨颅骨修补术后癫痫发作的危险因素。方法回顾性分析171例行颅骨修补术的颅骨缺损患者临床资料,探讨其术后癫痫发作的危险因素。结果 171例患者颅骨修补术后癫痫发作61例,癫痫发生率为35.7%。性别(OR=3.075,95%CI:1.318~7.176)、颅骨缺损区域凹陷率(Pd)(OR=0.024,95%CI:0.001~0.502)是颅骨缺损修补术后癫痫发作的独立危险因素。结论对于Pd较大、男性颅骨缺损患者,术后应密切观察并预防癫痫发作。

Objective To analyze the risk factors of epileptic seizures after cranioplasty.Methods A total of 171 patients with skull defect undergoing cranioplasty were analyzed retrospectively,and the risk factors related to post-cranioplasty seizures were investigated.Results Of the 171 patients,61 experienced seizures after cranioplasty with an incidence of 35.7%.Gender(OR=3.075,95%CI:1.318-7.176)and Pd(OR=0.024,95%CI:0.001-0.502)were the independent risk factors of seizures after cranioplasty.Conclusion The conditions of patients with higher Pd or male patients after cranioplasty should be closely assessed and prevention of epilepsy should be taken.