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甲状腺乳头状癌异常高回声晕的病理基础及预后判断价值

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摘要 目的探讨甲状腺乳头状癌异常高回声晕的病理基础及预后判断价值。方法选取经病理检查证实为甲状腺乳头状癌的493例患者为研究对象,术前确定结节边界状态。应用Adobe Photoshop CS6软件测量结节中心、异常高回声晕及周围正常甲状腺组织的灰度值,并在显微镜下观察异常高回声晕的病理基础;同时观察颈部淋巴结转移情况。结果根据二维超声声像图改变及灰度值测量结果,有异常高回声晕51例,无异常高回声晕442例。高回声晕组灰度值测量结果为异常高回声晕>正常甲状腺组织>结节中心(P<0.05)。显微镜下观察到伴有异常高回声晕患者的病理基础是癌细胞浸润伴炎性细胞及纤维组织的反应性增生。甲状腺乳头状癌患者总的淋巴结转移率为38.1%,其中伴有异常高回声晕组患者淋巴结转移率明显低于无异常高回声晕组(P<0.05)。结论异常高回声晕是肿瘤细胞向周边正常组织浸润的一种表现,在一定程度上提示肿瘤细胞远处转移力较弱,即恶性程度相对较低,预后相对较好。
出处 《浙江医学》 CAS 2018年第21期2385-2387,共3页 Zhejiang Medical Journal
基金 浙江省医药卫生科技计划项目(2018ZD050) 浙江省科技计划项目(2012C23095) 舟山市科技计划项目(2016C31042) 浙江省医学会临床科研资金项目(2015ZYC-A88) 舟山市医药卫生科技计划项目(2014T01)
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